Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, ...

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send ...

Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Calcineurin is a ubiquitous serine/threonine phosphatase that decodes calcium signals to regulate an array of cellular functions. Its activation requires calcium binding to calmodulin and the ...

Researchers at Texas A&M Health and collaborators have developed engineered CRAC channel inhibitory binders that can ...

Omaveloxolone (approved for Friedreich's ataxia) may help protect cells from stress and correct underlying dysfunction in SMA ...

BPC-157 and TB-500, originating from gastric and thymic sources respectively, both influence angiogenesis, cytoskeletal ...