Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, these molecules also play an important role in normal cellular signaling.

To function normally, nearly every cell in the human body relies on G-protein-coupled receptors (GPCRs) to receive and send ...

Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Phospholipase C (PLC) enzymes constitute a pivotal hub in cellular signalling by hydrolysing the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP₂) to generate the second messengers ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

BPC-157 and TB-500, originating from gastric and thymic sources respectively, both influence angiogenesis, cytoskeletal ...

Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...

This is a confocal section of an embryo where in one half (right; cells with cyan nuclei), adhesion is decreased by using an optogenetic tool. The left half is epithelialised with tricellular contacts ...

Researchers at Texas A&M Health and collaborators have developed engineered CRAC channel inhibitory binders that can ...

Type 1 diabetes is widely understood as an autoimmune disease, with the immune system attacking the insulin-producing beta ...