The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

On the left is a snapshot of single histone molecules (red) inside a cell nucleus (dotted line). On the right, we see the trajectories of these molecules’ movement over time. The colors show the path ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Rainbow Crops expects to announce a collaboration with a seed company on corn soon and is discussing additional partnerships ...

Genome-wide maps of chromatin structure in a cell-based model of breast cancer reveal chromatin reorganization accompanied by changes in transcription and epigenetic marks.