A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides new insights into human development. The research, published in eLife, is ...
In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly. Georgia Tech physicists are now helping explain why this happens, having ...
Scientists at St. Jude Children’s Research Hospital imaged cellular projections called cytonemes that transfer signals across long distances during development St. Jude Children’s Research Hospital ...
A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
Georgia Tech researchers demonstrated the mechanics behind neural tube closure, which can lead to severe or fatal birth defects if unsuccessful.
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