"A couple of years ago when we started to perform head-fixed chronic recordings in developing mice for another project, we recognized that activity within layer 2/3 of the medial prefrontal cortex ...

A brain structure called the amygdala, and its connections with another region, the prefrontal cortex, shape people’s experiences and social interactions. The discovery of a key molecular mechanism ...

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

This schematic outlines their analytical framework. The approach involves creating a validated developmental atlas of the dorsal prefrontal cortex from structural connectivity, then using these ...

A neuroimaging study of adolescents with ADHD found age-related increases in glutamate levels in the medial prefrontal cortex ...

During adolescence, the teen brain goes through dramatic changes which scientists are just beginning to better understand. For parents, teachers, and anyone who cares for a teenager—it is often ...

Before a person is even born, the brain has undergone intense expansion and growth in its complexity. This dramatic development continues into the first years of childhood. After an early boom period, ...

Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to ...