Frontiers

Segmentectomy vs Lobectomy in Early Lung Cancer: Re-evaluating Surgical Strategies After Randomized Trials

Recent randomized trials have profoundly reshaped the surgical management of early-stage non-small cell lung cancer. The ...
Hosted on MSN

AI agents advance Mendelian randomization research with new tools

Researchers are merging AI and Mendelian randomization (MR) to accelerate causal inference in biomedical research. New systems like MRAgent and AI-driven GWAS data fetchers automate literature review, ...
ascopubs.org

Bayesian Adaptive Randomization: Full of Promise With a Helping of Caution

Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits In the article that accompanies this ...
The New England Journal of Medicine

Prehospital Whole Blood in Traumatic Hemorrhage — A Randomized Controlled Trial

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...
The New York Times

What Are Clinical Trials, and How Do They Work?

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us. Credit...Ricardo Tomás Supported by By Nina Agrawal Nina Agrawal is a health ...
RAPS

Breakthrough Designation: Pivotal Trials Lack Randomization, Double-Blinding and Control Groups

Breakthrough Designation: Pivotal Trials Lack Randomization, Double-Blinding and Control Groups A review of all therapeutics receiving a breakthrough designation and approved from 2012 to 2017 found a ...