Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

In a basement lab in Brandeis' Rosenstiel building, a refrigerator-sized microscope dominates a small, windowless room. On its surface, it looks like a featureless white box. Yet inside, it's a study ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

A comparison of experimental annular dark field (ADF)-scanning transmission electron microscopy (STEM) and electron ptychography in uncorrected and aberration-corrected electron microscopes. In the ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

A new imaging technique enables atomic-scale clarity with compact, low-energy electron microscopes, making high-resolution microscopy more accessible worldwide. (Nanowerk News) A team of researchers ...

Responsive technique: Jonathan Peters using an electron microscope at Trinity College Dublin (Courtesy: Lewys Jones and Jonathan Peters/Trinity College Dublin) A new scanning transmission electron ...

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TEM works by accelerating electrons, typically with energies between 80 and 300 kV, and directing them through a specimen thin enough for electron transmission. Because of their very short wavelength ...