Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...

New tool helps uncover rare genetic mutations in common diseases, including Parkinson's

Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that ...
IEEE

Doing More With Less: A Survey of Data Selection Methods for Mathematical Modeling

Abstract: Big data applications such as Artificial Intelligence (AI) and Internet of Things (IoT) have in recent years been leading to many technological breakthroughs in system modeling. However, ...

AI framework helps identify new targets for CAR T cell therapy

Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers ...
Frontiers

Higher order versus pairwise interactions: A modeling debate

In recent years, network and complexity science has seen a massive surge in models using hypergraphs and simplicial complexes to represent higher-order ...

Machine learning helps identify six promising solvents for carbon dioxide electroreduction

Carbon dioxide (CO2) is a primary driver of climate change in Earth's atmosphere. At the State University of New York at ...